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 / Physicians

Drug shortage: bupivacaine HCl 0.25% and 0.5% with Epinephrine 1:200,000 X 20 mL vials

Date

The Issue: availability of bupivacaine HCl 0.25% and 0.5% with EPINEPHrine 1:200,000 X 20 mL vials remains limited and NH supply may not be sufficient each month to maintain usual needs.

Anticipated Resolution: December 2024

Clinical Use: anesthetic for local or regional anesthesia or analgesia 

Potential alternatives:

  • bupivacaine 0.25% and 0.5% injection (plain)
  •  lidocaine 1% and 2% with EPINEPHrine injection
  •  ropivacaine injection 

Further information and practice implications.

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