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Drug shortage: Piperacillin/tazobactam 2.25 g and 4.5 g vials

Date

The issue: Availability of piperacillin/tazobactam 2.25 g and 4.5 g vials remains limited in Canada and NH supply may not be sufficient to maintain usual needs at all sites. 

Anticipated availability: December 2024

Potential alternatives: 

  • Piperacillin/tazobactam 3.375 g vials 

 Alternative broad-spectrum IV antibiotics:

  • Amoxicillin/clavulanate 
  • Meropenem (formulary restricted) Alternative broad-spectrum IV antibiotics*:

Further information and practice implications.

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