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 / Physicians

Drug Shortage: Potential Etoposide IV Shortage

Date

There are ongoing supply interruptions of etoposide injectable in Canada.

Teva is the only Canadian supplier of preservative-free etoposide injectable. Teva has released supplies of etoposide, but it is on
allocation. BC Cancer centres have received supply. The ongoing supply is not yet secure and it is anticipated that there could be
further shortages lasting until December 2019.

Sandoz is the only Canadian supplier of etoposide injectable with preservatives. They do not anticipate supply to be available
again until December 2019.

Etoposide phosphate (Etopophos® - Bristol-Myers Squibb), which is not interchangeable with etoposide, may be available only
through the Health Canada Special Access Program.

Oral etoposide capsules, which have been available at restricted levels for the past few months, are available and no shortages
reported.

Further information and practice implications

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