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Drug shortage: Bupivacaine HCl 0.25% and 0.5% with Epinephrine 1:200,000 X 20 mL vials

Date

The issue: availability of bupivacaine HCl 0.25% and 0.5% with EPINEPHrine 1:200,000 X 20 mL vials remains limited and NH supply may not be sufficient each month to maintain usual needs.

Anticipated resolution: December 2024

Clinical use: Anesthetic for local or regional anesthesia or analgesia.

Potential alternatives:

  • Bupivacaine 0.25% and 0.5% injection (plain)
  • Lidocaine 1% and 2% with EPINEPHrine injection
  • Ropivacaine injection

Further information and practice implications.

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